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What is methylene blue?

Methylene blue (methylthioninium chloride) is a thiazine dye. An injectable prescription form (brand name ProvayBlue) is FDA-approved and indicated for pediatric and adult patients with acquired methemoglobinemia, given intravenously in clinical settings.

In a 2011 safety communication, the FDA noted that methylene blue is commonly used in diagnostic procedures and in clinical care for several other medical conditions.

The prescribing label lists important warnings, including serotonin syndrome with serotonergic drugs, hemolytic anemia in people with G6PD deficiency, and hypersensitivity reactions.

This article is general information, not medical advice. Talk to a qualified clinician about your situation.

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